Top Choice Hotels in Greenville for Memorable Stays

We checked thousands of reviews on and to find the best hotels for your stay
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Valery Van der Kruk

Updated: 07 January 2024 · 3 min

Nestled in the very heart of South Carolina, Greenville seamlessly blends Southern charm with modern urban life, making it a must-visit destination for travelers from all walks of life. As you plan your itinerary, ensuring comfortable and convenient accommodations is key to enhancing your experience in this vibrant city. Choice Hotels, with its myriad of options in Greenville offers travelers a perfect blend of comfort, convenience, and value, catering to every preference and budget.

In Greenville, the essence of Southern hospitality is palpable, not just in the city's attractions but also in the warm welcome you'll receive at Choice Hotels. Whether you're in town for a leisurely vacation, a business trip, or just passing through, these accommodations stand ready to serve as your home away from home. With amenities ranging from free Wi-Fi and breakfast to state-of-the-art fitness centers, Choice Hotels ensures your stay in Greenville is as enjoyable outside of your adventures as it is during them.

Finding the right hotel in Greenville doesn't have to be a daunting task. This article aims to simplify your search by highlighting the top Choice Hotels in the area. You'll get insights into not just the hotels' facilities and services but also tips on making the most of your stay in Greenville. So, whether you're drawn to the city for its lush parks, dynamic culinary scene, or historic landmarks, begin your journey with us as we explore the best Choice Hotels in Greenville ensuring your visit is nothing short of memorable.
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Our Top 6

(Sorted by rating & number of reviews)

1. Holiday Inn Express Greenville, An Ihg Hotel
2. Homewood Suites By Hilton Greenville, Nc
3. Hilton Greenville
4. Residence Inn By Marriott Greenville
5. Comfort Inn & Suites
6. Courtyard Greenville

Family-Friendly Choice Hotels in Greenville, SC

Check Availability

Greenville
Mar 10, 2026 - Mar 11, 2026

Holiday Inn Express Greenville, An Ihg Hotel

7.9

Good

(253 Reviews)

+ 59 photos
Located conveniently in the vibrant heart of Greenville an IHG Hotel, is a fantastic option for families looking for comfort and convenience. This hotel offers spacious, contemporary rooms with amenities tailored for family stays, such as in-room fridges and microwaves, perfect for late-night snacks or quick meals. The complimentary breakfast with a variety of options ensures a great start to your day. Additionally, the hotel boasts a beautiful outdoor pool, providing a fun and refreshing way for the family to unwind after a day of exploring Greenville. With its combination of cozy accommodations and attentive service, this hotel promises a stress-free and enjoyable stay for everyone.
Address: 909 Moye Blvd
Rating: Good 7.9 (253 Reviews)
Rooms: 124
Price: From 108$

Homewood Suites By Hilton Greenville, Nc

9.2

Good

(86 Reviews)

+ 44 photos
For families seeking a home away from home, Homewood Suites by Hilton Greenville offers spacious suites with fully equipped kitchens, allowing for a comfortable and flexible stay. The hotel's complimentary hot breakfast and evening socials during the week provide ample opportunity for family bonding over delicious meals. The outdoor pool and fitness center cater to both relaxation and active fun, ensuring that both kids and parents have a delightful stay. Its proximity to local parks and attractions means more family adventures with less travel time. Homewood Suites stands as a beacon of comfort and convenience, making it an excellent choice for families visiting Greenville.
Address: 424 Moye Blvd
Rating: Good 9.2 (86 Reviews)
Rooms: 118
Price: From 349$

Business-Ready Choice Hotels in Greenville, SC

Traveling for business often requires a specific set of amenities to ensure productivity and relaxation during your trip. In Greenville several Choice Hotels specialize in meeting the needs of business travelers. These hotels offer not just comfortable accommodations but also essential business facilities, such as meeting rooms, business centers, and high-speed internet access. Proximity to local business hubs and transport links further enhances their appeal. This section focuses on three hotels particularly well-suited for business visitors, combining convenience, comfort, and functionality to support a successful business journey to Greenville.

Hilton Greenville

8.6

Good

(164 Reviews)

+ 206 photos
Hilton Greenville is synonymous with premium business accommodations. Offering elegantly furnished rooms with ergonomic workstations and complimentary WiFi, the hotel caters to the needs of busy professionals. Business travelers will appreciate the ample meeting space and modern business center, ideal for hosting corporate events and meetings. The hotel's on-site restaurant serves a variety of savory dishes, ensuring a delightful dining experience without needing to leave the hotel. Additionally, Hilton Greenville's strategic location allows easy access to the airport and local business areas, making it a top choice for those on the business front.
Address: 207 Sw Greenville Blvd
Rating: Good 8.6 (164 Reviews)
Rooms: 142
Price: From 162$

Residence Inn By Marriott Greenville

7.9

Good

(93 Reviews)

+ 91 photos
Residence Inn by Marriott Greenville offers an exceptional stay for business travelers, combining the comfort of spacious suites with the functionality of home-like amenities. Each suite features a full kitchen and a well-lit work desk, providing the perfect environment for longer stays and productivity. The hotel boasts a versatile meeting room, ideal for small team sessions or client meetings. With a daily complimentary breakfast and weekday evening socials, networking and relaxation are conveniently within reach. Its proximity to major business districts and leisure spots in Greenville further enhances its appeal for business visitors seeking balance and convenience.
Address: 1820 West 5Th Street
Rating: Good 7.9 (93 Reviews)
Rooms: 97
Price: From 138$

Comfort Inn & Suites

7.3

Good

(654 Reviews)

+ 129 photos
Comfort Inn & Suites stands out as a top choice for families visiting Greenville. This hotel provides a warm and welcoming environment where every family member can find comfort and relaxation. With spacious rooms equipped with modern amenities, a swimming pool for fun-filled afternoons, and a complimentary breakfast to start your day right, Comfort Inn & Suites ensures your family's needs are well taken care of. Its central location also means easy access to Greenville's must-visit family attractions. Here, quality service meets comfort, making it an ideal base for your family's Greenville adventure.
Address: 3212 S Memorial Dr
Rating: Good 7.3 (654 Reviews)
Rooms: 89
Price: From 121$

Courtyard Greenville

8.4

Good

(343 Reviews)

+ 45 photos
Courtyard Greenville appeals to business travelers with its sleek design and comprehensive amenities. Each room is equipped with a spacious work desk and free high-speed internet, providing an ideal workspace for guests. The hotel features several meeting rooms, equipped with the latest technology, facilitating seamless business discussions and conferences. The on-site bistro offers healthy breakfast and dinner options, along with evening cocktails, perfect for informal meetings or relaxing after a day's work. Its location near major business centers in Greenville makes it an advantageous spot for business engagements and networking.
Address: 2225 Stantonsburg Road (Us 264)
Rating: Good 8.4 (343 Reviews)
Rooms: 115
Price: From 123$