Best Downtown Greenville Hotels

We checked thousands of reviews on and to find the best hotels for your stay
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Valery Van der Kruk

Updated: 14 March 2024 · 3 min

Nestled in the heart of South Carolina, Greenville boasts a vibrant downtown area that has become a focal point for travelers seeking both charm and adventure. The city’s urban core is peppered with a variety of downtown Greenville hotels, catering to every preference and budget. From luxurious boutiques to cost-effective options, these accommodations place visitors right in the midst of Greenville's bustling streets, brimming with art, culture, and culinary delights.

Choosing the right hotel in downtown Greenville can significantly enhance your travel experience. With most of these accommodations located just steps away from the iconic Falls Park on the Reedy, the Greenville Zoo, and a plethora of dining and shopping options, guests have the convenience of accessing the best of the city on foot. Insights into selecting a hotel that offers not just a place to stay, but an immersion into the local lifestyle, can be a game-changer for your trip.

As the city continues to evolve, so does the landscape of downtown Greenville hotels. Each property offers its own unique blend of Southern hospitality, modern amenities, and access to the pulse of Greenville's vibrant nightlife and entertainment scene. For those planning their visit, delving into recommendations and insights on the top downtown hotels can offer not just a sneak peek into what to expect, but a roadmap to experiencing Greenville to the fullest.
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Our Top 5

(Sorted by rating & number of reviews)

1. Holiday Inn Express And Suites Greenville
2. Americas Best Value Inn & Suites Greenville
3. Econo Lodge Greenville
4. Days Inn By Wyndham Greenville Ms
5. Harlows Casino Resort And Spa

Luxury & Comfort: Premier Downtown Greenville Hotels

Check Availability

Greenville
Dec 26, 2025 - Dec 27, 2025

Holiday Inn Express And Suites Greenville

+ 44 photos
For those seeking the reliability of a trusted brand with a touch of luxury, the Holiday Inn Express And Suites Greenville delivers. Located conveniently in downtown Greenville, this hotel combines comfort, convenience, and exceptional service. Rooms are designed with the modern traveler in mind, equipped with the latest technology and plush furnishings to ensure a restful night. Guests can start their day with a complimentary breakfast, featuring a wide selection of hot and cold items. The hotel also offers an outdoor pool and fitness center, allowing guests to relax or stay active during their stay. With its commitment to quality and guest satisfaction, the Holiday Inn Express And Suites stands as a beacon of luxury and comfort in downtown Greenville.
Address: 3090 Highway 82 East
Rooms: 73
Price: From 169$

Americas Best Value Inn & Suites Greenville

6.1

Good

(89 Reviews)

+ 19 photos
Americas Best Value Inn & Suites Greenville offers a reliable stay with an emphasis on value and comfort. This hotel is known for its friendly staff, clean rooms, and convenient location, making it a perfect base for exploring downtown Greenville. Guests can enjoy free Wi-Fi, comfortable bedding, and a calm atmosphere, ensuring a restful night’s sleep after a day of adventure. The hotel also features an outdoor pool, a rare find among budget-friendly establishments. With competitive rates and a commitment to quality, Americas Best Value Inn & Suites Greenville stands as a top choice for travelers who don't want to compromise on comfort while on a budget.
Address: 2700 Highway 82 East
Rating: Good 6.1 (89 Reviews)
Rooms: 80
Price: From 66$

Budget-Friendly Downtown Greenville Hotels

When it comes to exploring Greenville without breaking the bank, several downtown Greenville hotels offer comfortable accommodations at an affordable price. These hotels are characterized by their friendly service, clean rooms, and convenient locations that allow easy access to the city's attractions. Perfect for travelers who prioritize value and efficiency, these selections don't skimp on comfort or accessibility. The hotels in this section are chosen for their excellent balance of affordability and quality, ensuring that guests can enjoy their stay without financial worry. Let's delve into three hotels that represent the best in budget-friendly accommodations in downtown Greenville.

Econo Lodge Greenville

6.0

Good

(144 Reviews)

+ 47 photos
Econo Lodge Greenville is another great pick for travelers seeking budget-friendly downtown Greenville hotels. This hotel offers straightforward accommodations with an emphasis on comfort and convenience. Guests can expect rooms that are both cozy and functional, fitted with all the necessary amenities to ensure a pleasant stay. Added perks like complimentary breakfast and free parking make Econo Lodge an even more attractive option for those looking to maximize their savings. Its proximity to major Greenville attractions and businesses allows guests to save on transportation costs, making it ideal for both leisure and business travelers on a tight budget. Econo Lodge Greenville stands out as a beacon of affordability, providing a comfortable stay at an unbeatable price.
Address: 3080 Us 82 E.
Rating: Good 6.0 (144 Reviews)
Rooms: 77
Price: From 67$

Days Inn By Wyndham Greenville Ms

5.4

Good

(457 Reviews)

+ 50 photos
Days Inn By Wyndham Greenville MS stands as an emblem of affordability and convenience among downtown Greenville hotels. This hotel prides itself on offering guests a comfortable stay without the hefty price tag. Rooms are clean, spacious, and equipped with essential amenities such as free Wi-Fi and flat-screen TVs. Guests can also enjoy a complimentary breakfast, an added value that makes mornings a little easier. The hotel's location provides easy access to local dining and attractions, making it a fantastic choice for travelers looking to explore Greenville on a budget. With its combination of price, comfort, and location, Days Inn By Wyndham Greenville MS proves to be an excellent option for cost-conscious visitors.
Address: 2701 Highway 82 East
Rating: Good 5.4 (457 Reviews)
Rooms: 120
Price: From 81$

Harlows Casino Resort And Spa

+ 28 photos
Nestled at the edge of downtown Greenville offers a unique blend of excitement and relaxation. This hotel caters to guests looking for a vibrant escape without sacrificing comfort or luxury. Each room is crafted with opulence in mind, featuring modern decor and amenities that cater to every need. The resort is home to a world-class casino, providing entertainment around the clock, alongside live performances and events. The on-site spa is a sanctuary of serenity, offering a wide range of services from massages to beauty treatments. Harlow's Casino Resort and Spa stands out as a multifaceted destination, offering a sumptuous stay amidst the thrill of casino lights and the bliss of spa-induced calm.
Address: 4280 Harlows Blvd
Rooms: 105
Price: From 119$